NFL Best Bets: Predictions & Against The Spread Picks for Week 14

It’s Week 14 of the 2024 NFL season.

In San Francisco, the Bears face the 49ers in a battle of struggling offenses, where injuries and inconsistency could pave the way for a gritty, low-scoring affair.

Meanwhile over in Philadelphia, the Panthers take on the Eagles in a matchup where momentum and potential meet adversity.

Carolina’s underdog spirit clashes with the NFC juggernaut, with Bryce Young and his resurgent squad looking to defy expectations against an Eagles team riding high but potentially vulnerable after an emotional win.

Here are the wagers worth considering.

Week 14 Best Bet Prediction: Bears at 49ers Under 44.5

Both teams are limping into this matchup due to critical injuries on their offensive lines.

Chicago is navigating injuries to key players like center Ryan Bates and right tackle Darnell Wright, while San Francisco is also reeling, with injuries to left tackle Trent Williams and left guard Aaron Banks.

Not having these players at full health could wreak havoc on offensive rhythm and protection schemes, leaving both quarterbacks vulnerable and offenses sputtering.

For the 49ers, the issues extend beyond the trenches.

Their once-dominant ground game has hit a wall with Christian McCaffrey sidelined on IR and Jordan Mason unavailable, leaving their backfield alarmingly thin.

Without their rushing backbone, San Francisco’s offense has struggled to find consistency.

Brock Purdy’s recent performances underline these woes, with the quarterback averaging just 5.4 yards per attempt in back-to-back losses to Seattle and Buffalo.

Opposing defenses are taking notice, stacking the box and daring the 49ers to beat them through the air — a challenge they’ve yet to conquer, as evidenced by 7 turnovers in their last three games.

Scoring has become a tall order, with San Francisco managing 17 points or fewer in each of those contests.

On the other side, the Bears offense has been equally inconsistent, particularly on the road.

While Caleb Williams has shown promise under the new offensive coordinator with 5 touchdowns across his last two outings, Chicago’s away-game production remains a glaring weakness.

The Bears have been held scoreless in 7 of their last 12 road-game quarters including a first-half shutout against the Lions.

Brief sparks of offensive competence haven’t been enough to sustain drives, let alone carry them through an entire game.

Defenses are primed to dominate in this matchup.

The Bears defense, despite the team’s overall struggles, has shown the potential to disrupt opponents, while the 49ers defense has long been a cornerstone of their success and is poised to exploit Chicago’s road-game shortcomings.

When you factor in injuries on the offensive lines, a depleted 49ers backfield, Chicago’s road-game ineptitude, and offensive struggles for both teams, the case for the under 44.5 becomes clear.

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Week 14 Prediction: Bears +4.5 at 49ers

This isn’t just a tale of an underdog covering the spread. It’s about a team quietly building momentum and catching their opponent at the perfect time.

Caleb Williams is turning heads with his steady improvement.

Williams hasn’t thrown an interception in six consecutive games, a feat that highlights his maturity and decision-making under pressure.

Over his last two outings, he’s added 5 touchdowns to his stat line, signaling that he’s not just managing games but starting to take command.

With this upward trajectory, Williams has the tools to keep the Bears competitive against a 49ers team struggling to find its identity.

Although the Bears are currently 4-8, their record doesn’t tell the whole story. They’ve been within striking distance of some of the league’s heavyweights in recent weeks.

A narrow loss to the NFC-leading Detroit Lions showcased their ability to hang with the best. Add to the back-to-back heartbreakers against the Packers and Vikings, games decided by a razor-thin margin of four combined points, and it’s clear the Bears are just a few plays (and time outs) away from turning close losses into statement wins.

Plus, sometimes, change is the spark a team needs.

With head coach Matt Eberflus now out, the Bears could benefit from the “new coach effect,” where players rally with renewed focus and energy.

Interim coaching often brings a fresh approach, unburdened by the weight of previous failures, and Chicago seems primed to seize the moment.

Following their Thanksgiving game, the Bears have had ample time to regroup and prepare. In a league where rest and recovery are premium commodities, this extra time could make all the difference.

With fresh legs and a detailed game plan, the Bears enter this matchup better equipped to exploit the 49ers’ vulnerabilities.

San Francisco, meanwhile, has its share of woes.

With injuries to key offensive linemen and a depleted backfield, the 49ers have struggled to execute their game plan.

Brock Purdy’s passing game has been lackluster, and turnovers continue to haunt this offense. It’s an opportune moment for the Bears to strike while the iron is hot.

With a rising young quarterback, near-miss performances against quality opponents, a possible post-coaching change bump, and the advantage of extra rest, Chicago is positioned to stay within the number or even pull off the upset.

Take the Bears +4.5 and ride the wave of a team on the brink of a potential breakthrough.

Week 14 Prediction: Panthers +12.5 at Eagles

The Panthers may not have the wins to back it up, but their recent performances suggest a team on the upswing.

In back-to-back games, they’ve pushed strong opponents to the brink, narrowly falling to the Chiefs by three points and taking the Buccaneers into overtime.

These near upsets signal a growing competitiveness that defies their record and makes them a compelling underdog in this matchup.

Bryce Young is beginning to look like the franchise quarterback Carolina hoped for. His performance against Tampa Bay was a career highlight, with a season-high 298 passing yards, a touchdown through the air, and another on the ground.

Young’s ability to extend plays and make clutch throws hints at a player potentially finding his groove, and that confidence could be critical against a stout Eagles defense.

The Panthers defense has also turned up the heat. 9 sacks in two games, including five against Patrick Mahomes, is no small feat.

Jadeveon Clowney has been a game-wrecker, leading a pass rush that has disrupted even the most poised quarterbacks. If they can bring that same energy to Philadelphia, it might be enough to keep the high-powered Eagles offense in check.

Twelve points is a lot in the NFL, too much for a Panthers team that’s clearly playing with more fire and focus.

Even if the Eagles are the better team on paper, this kind of spread leaves plenty of room for Carolina to stay competitive, especially given their recent form. A double-digit cushion feels generous, given the way the Panthers have been clawing their way into games.

With Young showing flashes of efficiency, a reinvigorated defense, and a sizable spread that offers plenty of value, the Panthers have all the tools to cover +12.5.

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